Ontology
EC
Enzyme Nomenclature
The Enzyme Nomenclature (also known as the Enzyme Commission Code) is a species-agnostic controlled vocabulary for specific enzymes and an associated hierarchical classification into 7 main categories. The Enzyme Nomenclature is maintained by the [Nomenclature Committee](https://iubmb.org/about/committees/nomenclature-committee/) of the International Union of Biochemistry and Molecular Biology (IUBMB). A detailed history of the nomenclature since the 1950s can be found [here](https://iubmb.qmul.ac.uk/enzyme/history.html).
Source & access
- homepage enzyme-database.org HTTP 200
- download w3id.org HTTP 200
Portals & registries
| Source | ID | Version | Classes | Properties | Individuals | Loaded |
|---|---|---|---|---|---|---|
| OLS (EMBL-EBI) | ec | 2025-04-09 | 13,179 | 14 | 243,154 | 25 Oct 2026 |
Ontology IRI https://w3id.org/biopragmatics/resources/ec/ec.ofn
Version IRI https://w3id.org/biopragmatics/resources/ec/2025-04-09/ec.ofn
Languages en
Reused by (1)
HGNC
Also registered as
fairsharing: FAIRsharing.rfLD2u ols: ec wikidata.entity: Q741108
Automated evaluation
- Persistent identifier (F1)w3id.org+4
- Indexed in services (F4)3: OLS, Bioregistry, FAIRsharing+4
- Citable reference (F2)doi:10.1093/protein/gzx008+3
- Homepage reachableHTTP 200+3
- Artefact retrievable over HTTP(S) (A1)download HTTP 200+6
- Metadata persists in a registry (A2)Bioregistry+3
- Formal machine-readable format (I1)OWL, OBO+5
- Semantic-web IRIs (I2)OWL, OBO+3
- References other vocabularies (I3)imports 3: go, iao, ro+4
- Clear license (R1.1)CC BY 4.0+5
- Release provenance (R1.2)2025-04-09 (version IRI in the artefact)+4
- Community standards (R1.3)no independent compliance report (not on the OBO Dashboard)0
- Logical consistencynever checked by a reasoner0
- OWL 2 DL profileprofile not checked0
- Upper-ontology alignmentno BFO/COB/DOLCE import found0
- Standard relations (RO)imports RO+1
- ROBOT report: no errorsno ROBOT report available0
- ROBOT report: warning densityno ROBOT report available0
- Pitfall scan: no critical pitfallsno pitfall scan or ROBOT report yet0
- Recency2025-04-09 → 18.6 months (≤ 2 years)+2
- Release cadence (12 months)0 releases (OLS version IRI)0
- Documented adopting projects0 projects0
- Reused by other ontologies1: hgnc+1
- Community signalmax(stars 0 → 0, citations 13 → 1)+1
- Time since last activity1.5 years → 4 × max(0, 1.5 − 1)-2
- Inactive statusnot archived, legacy or inactive0
- Consistencynot yet checked by a reasoner0
FAIR subtotal 44/48 · earned 49/100 − 2 inactivity = 47/100 → grade D
History & changes 1 run
History starts with the first archived run; changes appear after the next evaluation.
| Run | Score | FAIR | Version evaluated | Terms | Snapshot |
|---|---|---|---|---|---|
| 26 Oct 2026, 03:31 UTC | 47 D | 44 | 2025-04-09 | 13,179 | JSON |
Provenance
Every fact on this page was fetched automatically. Each row shows where it came from and when. If a source fails, the last good value is kept and marked “carried forward”.
| Fact | Source | Retrieved |
|---|---|---|
| Homepage link check (HTTP 200) | enzyme-database.org | 26 Oct 2026, 02:53 UTC |
| Download link check (HTTP 200) | w3id.org | 26 Oct 2026, 02:53 UTC |
| Artefact header (version IRI) | raw.githubusercontent.com | 26 Oct 2026, 02:53 UTC |
| OLS classes, imports, version & release | ebi.ac.uk | 26 Oct 2026, 02:53 UTC |
| Bioregistry mappings, dependencies & reuse | bioregistry.io | 26 Oct 2026, 02:53 UTC |
| Crossref citations (doi:10.1093/protein/gzx008) | api.crossref.org | 26 Oct 2026, 02:53 UTC |
Run 2026-10-26T02-37-38Z · evaluator v2.0.0 · rubric v3.4 · entry.json · run snapshot
How to cite
- An update on the Enzyme Portal: an integrative approach for exploring enzyme knowledge (2017) · doi:10.1093/protein/gzx008 · 13 citations
- The ENZYME database in 2000 (2000) · doi:10.1093/nar/28.1.304