Ontology
TXPO
Toxic Process Ontology
Elucidating the mechanism of toxicity is crucial in drug safety evaluations. TOXic Process Ontology (TXPO) systematizes a wide variety of terms involving toxicity courses and processes. The first version of TXPO focuses on liver toxicity. The TXPO contains an is-a hierarchy that is organized into three layers: the top layer contains general terms, mostly derived from the Basic Formal Ontology.
Source & access
- homepage toxpilot.nibiohn.go.jp HTTP fetch failed
- repository github.com HTTP 200
- download purl.obolibrary.org HTTP 200
Portals & registries
| Source | ID | Version | Classes | Properties | Individuals | Loaded |
|---|---|---|---|---|---|---|
| OLS (EMBL-EBI) | txpo | 2022/12/07 | 9,406 | 148 | 0 | 25 Oct 2026 |
| OBO Dashboard | txpo | 2022-12-07 | 9,407 | — | — | 11 Dec 2025 |
Ontology IRI http://purl.obolibrary.org/obo/txpo.owl
Version IRI http://purl.obolibrary.org/obo/txpo/releases/2022-12-07/txpo.owl
Languages en en-us
Imports from (19)
BFO CHEBI CL CLO DOID EFO GO HP IAO MP NCBITaxon NCIT OBI OGMS OMIT PATO PR RO UBERON
Reused by (1)
ADO
- Logical consistency
- consistent · 0 unsatisfiable
- OWL 2 DL
- no
- ROBOT report
- 7 errors · 2,153 warnings · 112 info
- OBO principles
- FP01FP02FP03FP04FP05FP06FP07FP08FP09FP11FP12FP16FP20
- Axioms
- 81,084 · 41.11% entities reused
Also registered as
aberowl: TXPO bioportal: TXPO obofoundry: txpo ols: txpo ontobee: TXPO wikidata.entity: Q113014440
Automated evaluation
- Persistent identifier (F1)purl.obolibrary.org+4
- Indexed in services (F4)4: OLS, BioPortal, OBO Foundry, Bioregistry+5
- Citable reference (F2)doi:10.1038/s41598-020-71370-7+3
- Homepage reachableHTTP fetch failed0
- Artefact retrievable over HTTP(S) (A1)download HTTP 200+6
- Metadata persists in a registry (A2)OBO Foundry, Bioregistry+3
- Formal machine-readable format (I1)OWL+5
- Semantic-web IRIs (I2)OWL+3
- References other vocabularies (I3)imports 19: bfo, chebi, cl, clo, doid, efo, go, hp…+4
- Clear license (R1.1)CC BY 3.0+5
- Release provenance (R1.2)2022-12-07 (version IRI in the artefact)+4
- Community standards (R1.3)OBO principles: 5/13 checks pass+1
- Logical consistencyconsistent, 0 unsatisfiable classes (OBO Dashboard)+10
- OWL 2 DL profileoutside OWL 2 DL0
- Upper-ontology alignmentimports BFO+3
- Standard relations (RO)imports RO+1
- ROBOT report: no errors7 errors0
- ROBOT report: warning density2153 warnings / 9407 classes = 0.230
- Pitfall scan: no critical pitfallsno pitfall scan yet; ROBOT report has 7 errors0
- Recency2022-12-07 → 46.6 months (older / unknown)0
- Release cadence (12 months)0 releases (OLS version IRI)0
- Documented adopting projects0 projects0
- Reused by other ontologies1: ado+1
- Community signalmax(stars 1 → 0, citations 9 → 0)0
- Time since last activity3.9 years → 4 × max(0, 3.9 − 1)-12
- Inactive statusnot archived, legacy or inactive0
- Consistencyconsistent, no unsatisfiable classes0
- ROBOT report errors7 errors-3
FAIR subtotal 43/48 · earned 58/100 − 15 inactivity = 43/100 → grade D
Community adoption 0
No adopting projects documented yet.
Know a project that uses TXPO? Suggest it.
History & changes 1 run
History starts with the first archived run; changes appear after the next evaluation.
| Run | Score | FAIR | Version evaluated | Terms | Snapshot |
|---|---|---|---|---|---|
| 26 Oct 2026, 03:31 UTC | 43 D | 43 | 2022-12-07 | 9,406 | JSON |
Provenance
Every fact on this page was fetched automatically. Each row shows where it came from and when. If a source fails, the last good value is kept and marked “carried forward”.
| Fact | Source | Retrieved |
|---|---|---|
| Homepage link check (HTTP fetch failed) | toxpilot.nibiohn.go.jp | 26 Oct 2026, 03:27 UTC |
| Repository link check (HTTP 200) | github.com | 26 Oct 2026, 03:27 UTC |
| Download link check (HTTP 200) | purl.obolibrary.org | 26 Oct 2026, 03:27 UTC |
| Artefact header (version IRI) | raw.githubusercontent.com | 26 Oct 2026, 03:27 UTC |
| Git refs (commit 2358017) | github.com | 26 Oct 2026, 03:27 UTC |
| GitHub repository statistics | api.github.com | 26 Oct 2026, 03:27 UTC |
| OLS classes, imports, version & release | ebi.ac.uk | 26 Oct 2026, 03:27 UTC |
| OBO Foundry status, license & usages | obofoundry.org | 26 Oct 2026, 02:37 UTC |
| Bioregistry mappings, dependencies & reuse | bioregistry.io | 26 Oct 2026, 03:27 UTC |
| OBO Dashboard (checked 11 Dec 2025) | dashboard.obofoundry.org | 26 Oct 2026, 02:37 UTC |
| Crossref citations (doi:10.1038/s41598-020-71370-7) | api.crossref.org | 26 Oct 2026, 03:27 UTC |
Run 2026-10-26T02-37-38Z · evaluator v2.0.0 · rubric v3.4 · entry.json · run snapshot
How to cite
- Ontological approach to the knowledge systematization of a toxic process and toxic course representation framework for early drug risk management (2020) · doi:10.1038/s41598-020-71370-7 · 9 citations