Ontology
CHEBI
Chemical Entities of Biological Interest
Chemical Entities of Biological Interest (ChEBI) is a freely available dictionary of molecular entities focused on 'small' chemical compounds.
Source & access
- homepage ebi.ac.uk HTTP 200
- repository github.com HTTP 200
- download purl.obolibrary.org HTTP 200
Portals & registries
| Source | ID | Version | Classes | Properties | Individuals | Loaded |
|---|---|---|---|---|---|---|
| OLS (EMBL-EBI) | chebi | 256 | 238,150 | 48 | 0 | 25 Oct 2026 |
| TIB Terminology Service | chebi | — | 0 | 0 | 0 | — |
| OBO Dashboard | chebi | — | 224,691 | — | — | 8 May 2026 |
Ontology IRI http://purl.obolibrary.org/obo/chebi.owl
Version IRI http://purl.obolibrary.org/obo/chebi/256/chebi.owl
Languages en
Reused by (115)
ADO AGRO APOLLO_SV CHMO CIDO CLO COB CTENO CTO DDPHENO DIDEO DOID DPO DRON ECTO ENVO FBcv FOBI FOODON FYPO GENEPIO GENO GSSO HP IDO INO MAXO MCO MONDO MOP MP NBO NCRO OBA OBI OBIB OHD OMP ONS OPMI ORNASEQ PECO PHIPO PORO PR PROCO RBO RXNO SCDO STATO TO TXPO UBERON UPHENO VO WBPhenotype XPO ZP ADDICTO AFO AISM BAO BCGO BCO BMONT CAO CARO CDNO CHEMINF CHIRO CL CMPO COVOC DISDRIV ECAO ECO ECOCORE EFO ENM EUPATH EXMO FIDEO FLOPO FOVT GO HCAO ICEO ICO IDOCOVID19 IDOMAL MFMO MICRO MSIO NGBO OBCS OGSF OHMI OHPI OMIABIS OMIT ONE OVAE PATO PBPKO PCL PDRO PREFER PRIDE PSDO RO SLM SLSO VALUESETS VBO XCO
- Logical consistency
- consistent · 0 unsatisfiable
- OWL 2 DL
- no
- ROBOT report
- 0 errors · 400,509 warnings · 964 info
- OBO principles
- FP01FP02FP03FP04FP05FP06FP07FP08FP09FP11FP12FP16FP20
- Axioms
- 3,808,597 · 0.02% entities reused
Also registered as
aberowl: CHEBI biodivportal: CHEBI bioportal: CHEBI fairsharing: FAIRsharing.62qk8w obofoundry: chebi ols: chebi ontobee: CHEBI tib.ts: chebi wikidata.entity: Q902623
Automated evaluation
- Persistent identifier (F1)purl.obolibrary.org+4
- Indexed in services (F4)5: OLS, BioPortal, OBO Foundry, Bioregistry, FAIRsharing+5
- Citable reference (F2)doi:10.1093/nar/gkv1031+3
- Homepage reachableHTTP 200+3
- Artefact retrievable over HTTP(S) (A1)download HTTP 200+6
- Metadata persists in a registry (A2)OBO Foundry, Bioregistry+3
- Formal machine-readable format (I1)OWL, OBO+5
- Semantic-web IRIs (I2)OWL, OBO+3
- References other vocabularies (I3)imports 3: iao, ro, bfo+4
- Clear license (R1.1)CC BY 4.0+5
- Release provenance (R1.2)256 (version IRI in the artefact)+4
- Community standards (R1.3)OBO principles: 10/13 checks pass+2
- Logical consistencyconsistent, 0 unsatisfiable classes (OBO Dashboard)+10
- OWL 2 DL profileoutside OWL 2 DL0
- Upper-ontology alignmentimports BFO+3
- Standard relations (RO)imports RO+1
- ROBOT report: no errors0 errors+2
- ROBOT report: warning density400509 warnings / 224691 classes = 1.780
- Pitfall scan: no critical pitfallsno pitfall scan yet; ROBOT report has 0 errors+1
- Recency2026-10-06 → 0.6 months (≤ 3 months)+10
- Release cadence (12 months)0 releases0
- Documented adopting projects2 projects+2
- Reused by other ontologies115: ado, agro, apollo_sv, chmo, cido, clo…+4
- Community signalmax(stars 51 → 2, citations 1084 → 5)+5
- Time since last activity0.1 years → 4 × max(0, 0.1 − 1)0
- Inactive statusnot archived, legacy or inactive0
- Consistencyconsistent, no unsatisfiable classes0
FAIR subtotal 47/48 · earned 85/100 = 85/100 → grade A
Community adoption 2
- rhea-db.org
Rhea uses CHEBI to annotate reaction participants
Source: OBO Foundry registry - zfin.org
ZFIN uses CHEBI to annotate experiments
Source: OBO Foundry registry
Know a project that uses CHEBI? Suggest it.
History & changes 1 run
History starts with the first archived run; changes appear after the next evaluation.
| Run | Score | FAIR | Version evaluated | Terms | Snapshot |
|---|---|---|---|---|---|
| 26 Oct 2026, 03:31 UTC | 85 A | 47 | 256 | 238,150 | JSON |
Provenance
Every fact on this page was fetched automatically. Each row shows where it came from and when. If a source fails, the last good value is kept and marked “carried forward”.
| Fact | Source | Retrieved |
|---|---|---|
| Homepage link check (HTTP 200) | ebi.ac.uk | 26 Oct 2026, 02:43 UTC |
| Repository link check (HTTP 200) | github.com | 26 Oct 2026, 02:43 UTC |
| Download link check (HTTP 200) | purl.obolibrary.org | 26 Oct 2026, 02:43 UTC |
| Artefact header (version IRI) | ftp.ebi.ac.uk | 26 Oct 2026, 02:43 UTC |
| Git refs (commit 7b28409) | github.com | 26 Oct 2026, 02:43 UTC |
| GitHub repository statistics | api.github.com | 26 Oct 2026, 02:43 UTC |
| OLS classes, imports, version & release | ebi.ac.uk | 26 Oct 2026, 02:43 UTC |
| OBO Foundry status, license & usages | obofoundry.org | 26 Oct 2026, 02:37 UTC |
| TIB Terminology Service metrics | service.tib.eu | 26 Oct 2026, 02:43 UTC |
| Bioregistry mappings, dependencies & reuse | bioregistry.io | 26 Oct 2026, 02:43 UTC |
| OBO Dashboard (checked 8 May 2026) | dashboard.obofoundry.org | 26 Oct 2026, 02:37 UTC |
| Crossref citations (doi:10.1093/nar/gkv1031) | api.crossref.org | 26 Oct 2026, 02:43 UTC |
| Crossref citations (doi:10.1093/nar/gks1146) | api.crossref.org | 26 Oct 2026, 02:43 UTC |
Run 2026-10-26T02-37-38Z · evaluator v2.0.0 · rubric v3.4 · entry.json · run snapshot
How to cite
- ChEBI in 2016: Improved services and an expanding collection of metabolites (2015) · doi:10.1093/nar/gkv1031 · 1,084 citations
- The ChEBI reference database and ontology for biologically relevant chemistry: enhancements for 2013 (2012) · doi:10.1093/nar/gks1146 · 503 citations